White Sox vs. Guardians Predictions & Picks: Odds, Moneyline, Spread - May 22

Monday's game features the Cleveland Guardians (20-26) and the Chicago White Sox (19-29) matching up at Progressive Field in what is expected to be a competitive matchup, with a projected 6-4 victory for the Guardians according to our computer prediction. Game time is at 6:10 PM ET on May 22.
This contest's pitching matchup is set, as the Guardians will send Hunter Gaddis to the mound, while Jimmy Lambert (2-1) will answer the bell for the White Sox.
White Sox vs. Guardians Game Info & Odds
- When: Monday, May 22, 2023 at 6:10 PM ET
- Where: Progressive Field in Cleveland, Ohio
- How to Watch on TV: BSGL
- Live Stream: Watch this game on Fubo!
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White Sox vs. Guardians Score Prediction
Our pick for this matchup is Guardians 6, White Sox 5.
Total Prediction for White Sox vs. Guardians
- Total Prediction: Over 8.5 runs
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Explore More About This Game
White Sox Performance Insights
- In three games as the underdog over the last 10 matchups, the White Sox have a record of 1-2.
- In its previous 10 games with a total, Chicago and its opponents have combined to exceed the over/under just once.
- The White Sox's previous 10 matchups have not had a runline set by sportsbooks.
- The White Sox have been chosen as underdogs in 28 games this year and have walked away with the win seven times (25%) in those games.
- This season, Chicago has come away with a win five times in 24 chances when named as an underdog of at least +100 or worse on the moneyline.
- The moneyline set for this matchup implies the White Sox have a 50% chance of coming away with a victory in the contest.
- Chicago scores the 16th-most runs in baseball (203 total, 4.2 per game).
- White Sox pitchers have a combined ERA of 5.00 ERA this year, which ranks 27th in MLB.
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White Sox Schedule
Date | Opponent | Score | Pitching Matchup |
---|---|---|---|
May 17 | Guardians | W 7-2 | Mike Clevinger vs Peyton Battenfield |
May 18 | Guardians | L 3-1 | Dylan Cease vs Logan Allen |
May 19 | Royals | W 2-0 | Michael Kopech vs Zack Greinke |
May 20 | Royals | W 5-1 | Lucas Giolito vs Jordan Lyles |
May 21 | Royals | W 5-2 | Lance Lynn vs Carlos Hernandez |
May 22 | @ Guardians | - | Jimmy Lambert vs Hunter Gaddis |
May 23 | @ Guardians | - | Dylan Cease vs Logan Allen |
May 24 | @ Guardians | - | Michael Kopech vs Cal Quantrill |
May 25 | @ Tigers | - | Lucas Giolito vs Alex Faedo |
May 26 | @ Tigers | - | Lance Lynn vs Joey Wentz |
May 27 | @ Tigers | - | Mike Clevinger vs Michael Lorenzen |
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