Wednesday's contest at Guaranteed Rate Field has the Arizona Diamondbacks (83-74) taking on the Chicago White Sox (60-97) at 2:10 PM ET (on September 27). Our computer prediction projects a narrow 5-4 victory for the Diamondbacks, so expect a tight matchup.

The Diamondbacks will give the ball to Brandon Pfaadt (2-9, 6.08 ERA), who is eyeing win No. 3 on the season, and the White Sox will turn to Luis Patino.

White Sox vs. Diamondbacks Game Info & Odds

  • When: Wednesday, September 27, 2023 at 2:10 PM ET
  • Where: Guaranteed Rate Field in Chicago, Illinois
  • How to Watch on TV: NBCS-CHI
  • Live Stream: Watch this game on Fubo!

Bet on this matchup with BetMGM Sportsbook and use bonus code "GNPLAY" for special offers!

White Sox vs. Diamondbacks Score Prediction

Our pick for this matchup is Diamondbacks 5, White Sox 4.

Total Prediction for White Sox vs. Diamondbacks

  • Total Prediction: Under 9.5 runs

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Explore More About This Game

White Sox Performance Insights

  • In nine games as the underdog over the last 10 matchups, the White Sox have a record of 3-6.
  • In its previous 10 games with a total, Chicago and its opponents have combined to exceed the over/under on four occasions.
  • Oddsmakers have not posted a runline in any of the White Sox's past 10 matchups.
  • The White Sox have been underdogs in 107 games this season and have come away with the win 35 times (32.7%) in those contests.
  • This season, Chicago has come away with a win five times in 16 chances when named as an underdog of at least +155 or worse on the moneyline.
  • Sportsbooks have implied with the moneyline set for this matchup that the White Sox have a 39.2% chance of pulling out a win.
  • Chicago scores the third-fewest runs in baseball (634 total, four per game).
  • The White Sox have the 26th-ranked ERA (4.97) in the majors this season.

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White Sox Schedule

Date Opponent Score Pitching Matchup
September 20 @ Nationals L 13-3 Michael Kopech vs Josiah Gray
September 22 @ Red Sox L 3-2 Touki Toussaint vs Chris Sale
September 23 @ Red Sox W 1-0 Dylan Cease vs Nick Pivetta
September 24 @ Red Sox W 3-2 Mike Clevinger vs Kutter Crawford
September 26 Diamondbacks L 15-4 José Ureña vs Zach Davies
September 27 Diamondbacks - Luis Patiño vs Brandon Pfaadt
September 28 Diamondbacks - Touki Toussaint vs Ryne Nelson
September 29 Padres - Dylan Cease vs Nick Martínez
September 30 Padres - Mike Clevinger vs Michael Wacha
October 1 Padres - José Ureña vs Blake Snell